Importantly, given that other molecules are known to have receptors on fibroblasts, we asked how LIGHT might be similar or divergent compared with IL-13 and IL-17, two cytokines that have also been postulated to be involved in driving pathogenesis and inflammation in subsets of patients with diseases of the lung, including asthma, interstitial lung disease (ILD), idiopathic pulmonary fibrosis, and chronic obstructive pulmonary disease. The gene discussed is IL17A; the disease is asthma.