Of the 41 transcripts that were synergistically upregulated by the combination of LIGHT with IL-13 (Fig. 3), some, such as CCL2, CH25H, IL1RL1, EGR2, RGS4, and IL32, were strongly expressed in ILD fibroblast clusters 11 or 12, whereas others were randomly expressed in alternate clusters (Fig. S2A). Here, CH25H is linked to interstitial lung disease.