P2RY12 and diabetes mellitus: For vascular technical failure, the top models consistently identified the type of vascular closure device, TAVR device, sheath size, hostile score, aortic valve area, body mass index, body surface area, diabetes, previous cerebrovascular events, use of aspirin, use of a P2Y12 inhibitor, and TAVR indication (native TAVR vs valve-in-valve TAVR) as predictive features.