PDK1 and adrenal cortex carcinoma: We further divided patients into PDK1 high-expression group and PDK1 low-expression group based on the percentile (50%) of PDK1 expression, the results showed that only in KIRC patients, PDK1 was highly expressed and had a longer survival time, while in ACC,CESC,GBMLGG,LGG and SARC patients, PDK1 was highly expressed and had a shorter survival time (P < 0.05, Fig 6D-6I).