Ultimately, demonstrating hearing recovery through in vivo modulation of FASLG expression—such as knockdown or overexpression in age-related hearing loss (ARHL) animal models like C57BL/6 mice, followed by auditory brainstem response (ABR) testing—will be essential to provide definitive evidence for its functional role and therapeutic potential in ARHL. The gene discussed is FASLG; the disease is presbycusis.