Thereafter, the entire APC complex is internalized within the targeted cancer cells and only unleashes its phototoxic effects post‐light exposure (690 nm) through the generation of ROS, which ultimately cause tumor destruction through apoptotic, necrotic, and ICD (Table 1) [8, 35, 52, 61, 291, 292, 293, 294, 295]. Here, APC is linked to neoplasm.