ePWV, a simpler and more feasible alternative derived from age and MBP, has demonstrated a strong correlation with cfPWV and has been independently associated with death and cardiovascular events in the general population18, 22, 27, 36, 40 and other specific populations, including individuals with hypertension,20 diabetes,19 stroke,14 chronic kidney disease, and atherosclerotic CVD.28 This evidence concerns the gene MBP and hypertensive disorder.