But in the case of MycC/+ lymphomas, a persistent, highly reduced growth rate was apparent for the same tumor after Myc gene dosage reduction (lower slope, Figure 6B); this differential effect of the induced Myc haplo-insufficiency remained evident even when tamoxifen treatment was delayed for a week after allografting to ensure efficient tumor engraftment (Figure 6C). The gene discussed is MYC; the disease is lymphoma.