Another study found that the decreased myogenicity of DMD patient biopsy-derived MuSCs was associated with the dysregulation of epigenetic regulatory factors, such as chromobox protein homolog 3 (CBX3), histone variants H2AZ2 and H3F3B, and structural maintenance of chromosomes 3 (SMC3). Here, CBX3 is linked to Duchenne muscular dystrophy.