The clinical features are varied and nonspecific, with fever exceeding 39°C, asymmetric arthralgia/arthritis, skin rash (salmon pink rash), sore throat, enlarged lymph nodes, hepatosplenomegaly, and inflammatory findings (neutrophilic leukocytosis, increased erythrocyte sedimentation rate (ESR), elevated C-reactive protein (CRP), impaired liver function, and hyperferritinemia) [1,2]. This evidence concerns the gene CRP and arthritic joint disease.