BAX and neuroblastoma: Wang X et al. suggest that PF significantly improves the Glu-induced decrease in SH-SY5Y cell viability in human neuroblastoma cells by affecting the expression of Bax/Bcl2, cleaved caspase-3, and cleaved caspase-9, suggesting that PF significantly reduces cell apoptosis and exerts neuroprotective effects through the Bax/Bcl2 pathway (Wang X. et al., 2021) (Figure 4).