In pre-infection samples (day 66), animals receiving the combination of live dpB and SARS-CoV-2 vaccination (group 4) showed statistically higher levels of IL-6 and IL-10, than inactivated dpB-SARS-CoV-2 vaccine group (group 2) (M-W, pb< 0.001; M-W, pb=0.040) (Figures 3A, E). This evidence concerns the gene IL6 and infection.