Interferon-induced transmembrane protein 1 (IFITM1), a member of the interferon-induced transmembrane protein family, has been implicated in various biological processes, including anti-proliferation, cell adhesion regulation, and immune monitoring in digestive tract cancers such as esophageal, gastric, liver, and colorectal cancers (9). The gene discussed is IFITM1; the disease is colorectal cancer.