TGM2 and Cowden disease: Despite the recognized burden of CD in neighboring regions, there is a paucity of data on its prevalence in the Gulf region, including Qatar.3 CD diagnosis relies on a two-step process: serum serological screening using anti-tissue transglutaminase IgA (anti-tTG IgA) and anti-endomysial IgA (anti-EM IgA antibodies), followed by duodenal biopsy for histological confirmation.