For illustration, consider a patient with the following profile: NLR (x1)=3 (50 points), BMI (x2)=23 kg/m2 (40 points), Tumor size (x3)=1.8 cm (20 points), Lymph node metastasis (x4)=0 (25points), CEA (x5)=5.7 ng/mL (45 points) and Age (x6)=74 years (40 points). Here, CEACAM5 is linked to neoplasm.