MAPT and early-onset autosomal dominant Alzheimer disease: For instance, tau can be present in various types of NDDs (i.e., tauopathies), such as Alzheimer’s Disease, frontotemporal lobar degeneration (FTLD, formerly referred to as frontotemporal dementia – FTD), progressive supranuclear palsy (PSP), Parkinson’s Disease, and corticobasal degeneration (CBD) (55).