VWF and dementia: Plasma levels of VWF were significantly associated with changes in volumes of the hippocampus (Coefficients [95% CIs] = 0.016 [0.004, 0.027]; p value = 0.009; Figure 4A), entorhinal cortex (Coefficients [95% CIs] = 0.031 [0.014, 0.048]; p value < 0.001; Figure 4B), fusiform gyrus (Coefficients [95% CIs] = 0.047 [0.008, 0.085]; p value = 0.017; Figure 4D), and ventricles (Coefficients [95% CIs] = −0.380 [−0.558, −0.203]; p value < 0.001; Figure 4E) over time among older adults without dementia.