Catatonia has occasionally been reported to co-occur with Parkinson’s disease, dementia with Lewy bodies and progressive supranuclear palsy.67-76 In some cases, catatonia has been reported in the context of Parkinson’s disease after withdrawal of pro-dopaminergic medications.72,76 Parkinsonism and catatonia have also been noted to co-occur in certain genetic syndromes, including in Rett syndrome77 and in a patient with variants of the SHANK3 and SYNJ1 genes.78 These reports are suggestive but by no means conclusive. The gene discussed is SHANK3; the disease is Parkinson disease.