After targeted therapy, the CRP concentration (mean 10.64, SD 15.37 mg/L) in the group with no cognitive disorder was also significantly lower than that of the group with cognitive disorder (mean 20.09, SD 27.37 mg/L), and there was a significant difference between the 2 groups (z=−1.975; P=.048). Here, CRP is linked to Cognitive impairment.