[94, 95], Eno1 (regulated by P400 and is a glycolytic enzyme essential for metabolism and implicated in cancer progression) [96], and Krit1 (regulated by SRCAP and stabilizes endothelial cell junctions and is linked to vascular integrity and cerebral cavernous malformations) [97, 98], and analyzed their transcriptional dynamics using multiple assays, including Pol II ChIP-seq and TT-seq. Here, ENO1 is linked to famililal cerebral cavernous malformations.