AKT1 and endometriosis: Likewise, Tanshinone IIA has been reported to alleviate osteoclastogenesis in ovariectomized mice by dampening NF‐kB and AKT signaling pathways [37], and also to inhibit PI3K/AKT/mTOR signaling in endometriosis by modulating angiogenesis, invasion, and adhesion [38].