Conversely, comparing the differential gene expression between PD-L1 negative ATCs versus PD-L1 negative PDTCs, we observed downregulation of RORC and PLA2G6 (p-value < 0.05) only in the ATC group (Supplementary Fig. 3b). The gene discussed is CD274; the disease is Ehlers-Danlos syndrome, musculocontractural type.