CAMKK1 and type 2 diabetes mellitus: Therefore, while our findings highlight a robust association between CAMKK1 levels and T2DM status, longitudinal and mechanistic studies will be essential to establish whether CAMKK1 plays an etiological role or reflects downstream alterations in energy and glucose metabolism, as well as whether CAMKK1 elevation may be described as either adaptive or maladaptive in nature.