CAMKK1 and obesity due to melanocortin 4 receptor deficiency: However, in contrast to differences between individuals with T2DM and controls, differences in CAMKK1 serum levels between individuals with obesity and controls (age and sex‐adjusted ANCOVA, effect of diagnosis, F = 28.805, p < 0.001, post hoc comparison Tukey‐adjusted p = 0.001) were not significant after accounting for BMI (age, sex and BMI‐adjusted ANCOVA, Tukey‐adjusted p = 0.292, Table 1).