While BRCA1 and BRCA2 mutations are well-known germline mutations associated with an increased risk of breast cancer, several other non-BRCA genes can also harbor germline mutations linked to breast cancer susceptibility—for example, TP53, PTEN, STK11, PALB2, CHEK2, ATM, RAD51C, and RAD51D genes (Wang et al., 2021). Here, CHEK2 is linked to breast cancer.