We also noted almost exclusive upregulation of the scavenger receptor Cd36 in BAM_7 after TBI which aligns with a recent report showing that Cd36 positive macrophages in mouse model of ischemic stroke exhibited enhanced expression of phagocytic and lipid-handling genes.40 Taken together, these data suggest that high expression of Cd36 may be a marker of lipid-loaded monocyte population after TBI. Here, CD36 is linked to ischemic stroke.