GCG and Hypoglycemia: From mean values of 4.48 pmol/L in the tirzepatide group and 7.45 pmol/L in the placebo group at a target PG 100 mg/dL, the primary analysis showed that increases in mean glucagon concentration in response to induced hypoglycemia from the target PG 100 mg/dL to nadir did not differ between treatments (Table 2).