In our investigation, we conducted a comprehensive assessment of tumor growth using histological analysis via H&E staining, along with immunohistochemical markers CD3 (reflecting infiltrating T cells) and CD68 (indicating an inflammatory response or the presence of tumor-associated macrophages) in mice bearing mIDH1 tumors subjected to treatment with ATG7i-SPNP + IR. This evidence concerns the gene CD68 and neoplasm.