IDH1 and glioma: We found that mIDH1 mouse glioma NS had significantly higher quantities of mitochondria in the fission state (mean ± SEM = 192 ± 20 mitochondria in fission state) when compared to WT-IDH1 mouse glioma NS (mean ± SEM = 103 ± 15 mitochondria in fission state; P < 0.005; Fig. 5l).