Consistent with the SLE data (Figure 2A), the CXCR5+ PD-1hi population from these patients was predominantly composed of C0 (Tfh), whereas sorted CXCR5− PD-1hi cells contained cells that clustered in C1 (Th1), C2 (Th2), and C4 (Th17). Here, CXCR5 is linked to systemic lupus erythematosus.