This includes CXCR4+ extrafollicular helper T cells in murine lupus (42), as well as CXCR5− Tfh-like cells in lungs of mice with chronic Ag-driven inflammation (43), and T resident helper cells observed in lungs of mice with influenza (44, 45). The gene discussed is CXCR5; the disease is systemic lupus erythematosus.