By day 7 of tumorigenesis, the tumors of untreated mice tended to invade the muscles and the treated group showed higher percentages of neutrophils in the tumor (Fig. 10H), increased expression of neutrophil CXCR2 (Fig. 10I), enhanced production of NETs (Fig. 10J), and elevated concentration of NE protein in the tumor tissue grinding fluid (Fig. 10K) compared to the untreated group (Fig. 10H and I). The gene discussed is CXCR2; the disease is neoplasm.