In this approach, radiolabeled peptide ligands targeting CCK2R can selectively accumulate in tumor regions and serve both diagnostic and therapeutic purposes: 68Ga, a positron-emitting radionuclide, enables high-resolution positron emission tomography (PET) imaging for accurate tumor localization, whereas 177Lu, a β-particle emitter, induces DNA single-strand breaks, thereby enabling targeted radiotherapy and promoting tumor cell death 5, 6. This evidence concerns the gene CCKBR and neoplasm.