Over time, tumor uptake steadily increased, with [68Ga]Ga-DOTA-CCK2R-dimer demonstrating significantly greater tumor uptake than [68Ga]Ga-DOTA-CCK-66 did at both 1 h (12.80 ± 2.05 vs. 6.79 ± 1.50; p = 0.015) and 2 h (20.19 ± 3.31 vs. 9.53 ± 2.38; p = 0.011) (Figure 2E); notably, blocking with excess of unlabeled ligand significantly reduced the uptake of [68Ga]Ga-DOTA-CCK2R-dimer after 1 h to 3.91 ± 1.23 (p = 0.002) and that of [68Ga]Ga-DOTA-CCK-66 to 2.35 ± 1.18 (p = 0.017), further confirming receptor-specific accumulation (Figure 2E). The gene discussed is CCKBR; the disease is neoplasm.