ANGPTL4 and neoplasm: Angiogenesis initiated from Tumor activated-endothelial cells (TECs), resulting in the production of vascular endothelial growth factor A (VEGF-A), angiopoietin-like 4 (ANGPTL4), placental growth factor (PIGF), and platelet-derived growth factor B (PDGF-B), all of them, contribute to the endothelial cell proliferation, migration, and capillary formation.