Thus, it is not surprising that rat and mouse strains engineered to carry loss of function or knockouts of Pink1 not only recapitulate motor deficits of PD (Dave et al., 2014; Lamberty et al., 2023; Soto et al., 2024a) including those involving orofacial movements and vocalization (Grant et al., 2015; Hoffmeister et al., 2021; Johnson et al., 2020; Kelm-Nelson and Gammie, 2020; Kelm-Nelson et al., 2018; Marquis et al., 2020), but also show non-motor impairments in cognition and memory (Desai et al., 2025; Desai et al., 2025; Pinizzotto et al., 2022; Soto et al., 2024b). Here, PINK1 is linked to Parkinson disease.