Although misexpression studies can sometimes be difficult to interpret, in this case we were not looking for endogenous function of ATXN3 (which is not conserved in Drosophila) but rather using mutATXN3-(CAG)84 as a reporter of neuronal populations for which normal function is required for smooth motor movements, in light of knowing that its pan-neuronal expression causes tremor (Wu et al., 2019). The gene discussed is ATXN3; the disease is Tremor.