AHR and glycogen storage disease VI: While we demonstrated that phagocytosis of RBC by microglia is enhanced by BrB and ITE (AhR ligands) and that AhR deficiency in microglia negatively impacted phagocytosis, Zahringer et al. when studying acute graft-versus-host disease observed that microglia in culture showed deficient phagocytosis toward microbeads, upon exposure to AhR ligand 6-formylindolo(3,2-b)carbazole.74 This discrepancy could be related to the use of different AhR ligands or phagocytic targets.