These results are in line with previous studies demonstrating that dihydroartemisinin suppresses FGFR3 and HRAS expression and induces apoptosis in cancer models, and that Artemisia annua extracts enhance TP53 expression in breast and gastric cancers through ERK1/2-mediated pathways [26, 39, 40]. Here, FGFR3 is linked to gastric cancer.