,24,25 Phosphodiesterase 7A (PDE7A) belongs to the PDE7 subfamily26 and hydrolyzes the second messenger 3′,5′-cyclic adenosine monophosphate (cAMP),27 which plays a role in many biological processes, including cancer growth, migration, and invasion; cell-cycle regulation; transcriptional activation; and apoptosis.28 This evidence concerns the gene PDE7A and cancer.