VDR and myeloid sarcoma: Moreover, the ApaI SNP (rs7975232 C/A), situated within an intron region of the VDR gene on chromosome 12, exhibited a significant association with MS susceptibility in terms of allele frequencies, indicating an overall estimated odds ratio of 1.93 (χ2 (2, N = 418) = 4.14, P-value = 0.04).