Similarly, the PXN-AS1-L isoform—containing exon 4—directly interacts with the 3′ untranslated region (3′UTR) of PXN mRNA, inhibiting its degradation by the miR-24–AGO2 complex and consequently upregulating PXN expression in hepatocellular carcinoma [41]. This evidence concerns the gene AGO2 and hepatocellular carcinoma.