CD40LG and pulmonary tuberculosis: On the other hand, reports on Mycobacterium tuberculosis infections describe that serum anti-PL antibody levels, specially IgM and total IgG, may serve as effective biomarkers for the diagnosis of pulmonary tuberculosis and monitoring the efficacy of anti-tuberculosis treatment, thus providing an alternative to standard methods, as anti-PL IgM levels significantly decreased after drug treatment.41