TARDBP and Alzheimer disease: Transactive Response (TAR) DNA‐binding Protein 43 kilodaltons (TDP‐43) is a ubiquitously expressed heterogeneous ribonucleoprotein (hnRNP) implicated in the pathophysiology of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), in addition to limbic‐predominant age‐related TDP‐43 encephalopathy (LATE) Alzheimer's disease (AD) (Arai et al., 2006; Kabashi et al., 2008; Neumann et al., 2006; Sreedharan et al., 2008).