Furthermore, correlation analyses revealed that particularly in ALD‐related decompensated cirrhosis, specific IgM titres to MDA and MAA positively correlate with serum AST (IU/L) and hepatic venous pressure gradients (HVPG [mmHg]), a relevant predictor of ALD outcome [25], while a significant correlation was found with IgG levels in the compensated stage (Figure 1E,F and S1I,J; Table S1). Here, CD40LG is linked to Cirrhosis.