It is also implicated in the regulation of tumor progression in CRC through the E‐cadherin/β‐catenin‐mediated adherent junction or cell–cell contact, and the epithelial‐mesenchymal transition (EMT) via the TGF‐β pathway or transcription factors such as Slug and Snail [5, 25]. The gene discussed is CDH1; the disease is colorectal carcinoma.