Simple effect analysis showed that the activation of oxy-Hb in the left DLPFC was significantly higher in positive emotional valence than in negative emotional valence for the groups with depression-high resilience (Bonferroni-corrected p < 0.05/4) and healthy-low resilience (Bonferroni-corrected p < 0.05/4), whereas there were no significant differences between the two emotional valences for the groups with depression-low resilience (p > 0.05) and healthy-high resilience (p > 0.05) (Figure 3). The gene discussed is GSTM1; the disease is major depressive disorder.