The univariate logistic regression analysis revealed that improvement in hypertension was significantly associated with BMI (p=0.043), postoperative/preoperative PRA ratio (p<0.001), preoperative AT II (p<0.001), circulatory diseases (p<0.001), and preoperative BP (p<0.001) (Table 2 and Figure 4). Here, S100A6 is linked to Hypertension.