6 genes (BGN, DDIT4, MIF, SLC2A1, STC2, and TGFBI) were upregulated, and 10 genes (CA12, CITED2, MT1E, MT2A, NEDD4L, PCK1, PLAC8, PPARGC1A, SELENBP1, and SRPX) were downregulated in CRC. The gene discussed is PCK1; the disease is colorectal carcinoma.