Through the integration of scRNA-seq and single cell genomic sequencing, transcriptional profiles of normal endocrine cells (gonadotrophs, somatotrophs, and lactotrophs) to cognate tumor cells revealed several tumor-related genes such as adhesion molecule with Ig like domain 2 (AMIGO2), zinc finger protein 36 (ZFP36), BTG anti-proliferation factor 1 (BTG1), and disks large MAGUK scaffold protein 5 (DLG5) (34). The gene discussed is AMIGO2; the disease is neoplasm.