Notably, the GZMA CD4 T cell subset exhibited elevated expression of genes associated with effector and cytolytic functions in CD4 T cells, including GZMA, GZMH, GZMM, and PRDM1, while also showing moderate expression of anti-cancer-related genes such as IFNG, PRF1, and TNFSF10. This evidence concerns the gene GZMM and cancer.