Comparing the DEGs between TEM in HP and LCP patients, we found that 14 out of these 17 genes (FOXN3, FOXO1, FOXP1, INPP4A, KLF12, KMT2C, MAP3K5, MLLT3, NEAT1, NFATC2, PRKY, RALGAPA1, RASA3, SYNE2, SYNE2, ZBTB20, and ZEB2) followed the transition from CXCR3lo TEM to CXCR3+ TEM and finally to CCL4+ TEM. Here, SYNE2 is linked to Legg-Calve-Perthes disease.