TNF and Pleural effusion: Various Th1/Th2 ratios, including TNF-α/IL-10, TNF-α/IL-4, TNF-α/IL-5, IFN-γ/IL-4, and IL-12/IL-4, were significantly lower in the MPE of LCP than in the pleural effusion of HP (Figure 6H and sFigure 5A and 5B).