This result demonstrates a critical connection that implies coronaviruses may interfere with the miRNA biogenesis pathway (Schütz and Sarnow, 2006; Mockenhaupt et al., 2011) and validates the findings that AGO2, Dicer, and Drosha were considerably decreased in COVID-19 victims compared to the control participants (Casseb et al., 2016). The gene discussed is AGO2; the disease is COVID-19.