Notably, these 10 feature genes were significantly enriched in several key pathways related to immune regulation, inflammation, and cellular stress responses, such as “the interleukin-10 signaling pathway”, “chemokine receptor and ligand binding”, “peptide ligand-receptor interaction”, “TNF receptor superfamily members mediating non-canonical NF-κB signaling”, “the unfolded protein response (UPR) “, and “the PI3K/AKT signaling pathway in cancer” (Supplementary Figure 5B, Supplementary Table 6). Here, NFKB1 is linked to cancer.