The protein expression level of FAK was up-regulated in 40% (13/31) tumor tissues (Supplementary Figure 6), including Cholangio carcinoma, Lymphoid Neoplasm Diffuse Large B-cell Lymphoma, Head and Neck squamous cell carcinoma, Stomach adenocarcinoma (STAD), Pancreatic adenocarcinoma (PAAD), Thymoma (THYM), Esophageal carcinoma, and Liver cancer (LIHC) (Figure 7A, Supplementary Figures 6, 7). Here, PTK2 is linked to head and neck squamous cell carcinoma.