PTK2 and liver cancer: Among these, 2-((2-((3-(Acetamidomethyl)phenyl)amino)-5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-methylbenzamide (THY-10A62 or 16c) displayed an IC50 value of 12 nM against FAK kinase activity and half-maximal inhibitory concentrations of 2.39 μM and 10.07 μM against the liver cancer cell lines YY8103 and SMMC7721, respectively (27).