The protein expression level of FAK was up-regulated in 40% (13/31) tumor tissues (Supplementary Figure 6), including Cholangio carcinoma, Lymphoid Neoplasm Diffuse Large B-cell Lymphoma, Head and Neck squamous cell carcinoma, Stomach adenocarcinoma (STAD), Pancreatic adenocarcinoma (PAAD), Thymoma (THYM), Esophageal carcinoma, and Liver cancer (LIHC) (Figure 7A, Supplementary Figures 6, 7). This evidence concerns the gene PTK2 and carcinoma of esophagus.