Correlation analysis via GEPIA2 showed that PRKAG1 was significantly positively correlated with BCDIN3D (R=0.60, P<0.001) and KBTBD4 (R=0.59, P<0.01) (Figures 5G, H), suggesting potential synergistic effects of these proteins in HCC. This evidence concerns the gene KBTBD4 and hepatocellular carcinoma.